r/TTC_PCOS • • 16d ago

Monthly Medication Thread

1 Upvotes

This thread is the place to post any questions or information pertaining to a medicated cycle including Letrozole, Clomid, IUI, injectables, Progesterone, and anything else used to induce ovulation or support a cycle.

Please be mindful in your responses - if someone does not solicit a success response, DO NOT share a pregnancy outcome.


r/TTC_PCOS • • 6d ago

Success Sunday - Week of October 11, 2026

1 Upvotes

Get a BFP? Post about it here! In your post please include if you had regular cycles on your own, any medications you are taking, supplements, and how long you were trying. Feel free to post links to your chart, photos of sticks, etc. Please feel free to graduate on over to our sister subs and congratulations! Success stories posts are now weekly! Please click here to search for previous threads.


r/TTC_PCOS • • 11m ago

BBT and ovulation

• Upvotes

Hello everyone. I am so desperate.

14/10 I had a positive LH test (temperature 36,4). 15/10 36,1 , 16/10 36,6 , 17/10 36,5 and today 18/10 36,1.

What is going on? I feel helpless


r/TTC_PCOS • • 4h ago

Discussion BBT for dummies?

1 Upvotes

BBT?

Hi all— I’m super duper new to all of this. We’re having secondary infertility. I was able to conceive my first two kids by just “going with the flow” and my youngest is three… we’ve done unprotected baby dancing for years in hopes it would happen again, but just hasn’t and we’re ready to have another.

Can someone explain BBT to me like I’m 5? I understand how OPKs work. I definitely don’t ovulate regularly and have started Ovasitol about a week ago.

I got my period just recently and am on CD2. I get my period about every 29-38 days or so. Very give or take on what my body decides it wants to do.


r/TTC_PCOS • • 16h ago

Seeking Success Staying positive after failed medicated cycles

8 Upvotes

I just finished my 2nd medicated and monitored cycle of letrozole. This cycle looked very positive, I had 3 mature follicles (24mm, 18mm, & 18mm). Uterine lining was thick and progesterone looked great on it own. Went through the two week wait and just got my negative with my period arriving the next day. How do you stay positive and keep going after everything went right but the cycle still failed? How many medicated cycles until you were successful?


r/TTC_PCOS • • 1d ago

Seeking Success I took one big dose letrozole cd3

1 Upvotes

Doctor gave me 1 big dose 20 mg letrozole on cd3
İs there anyone tried this one dose ?


r/TTC_PCOS • • 1d ago

Starting TTC next week with PCOS and endo. Scared and just looking for good vibes ✨

2 Upvotes

So happy to have found a community for me. I’m 23 and have PCOS and endo.

As far as PCOS goes, I have high follicle count, 6.8amh, and very irregular cycles (100-200 days). My hormone levels are normal as well as normal CD3 labs, prolactin, BMI, no hirsutism.

In terms of endo, I had laparoscopic surgery with an endo specialist a few weeks ago. They found one 0.5-1mm endo lesion on my rectal area but did not excise it due to bleeding risk. They called it “stage 0.5 endo.” Tubes looked good.

Now I’m starting 2.5mg Letrozole medicated cycles next week. I pray it works….

Both my paternal aunts had endo and failed Clomid and IVF in the 1990s. My dad was the only one to have kids of the three siblings. My mother’s family had no known fertility issues. I’m starting my own journey now and I’m hopeful but so scared. I don’t have any specific questions but just want to connect with this group and express gratitude that it exists!


r/TTC_PCOS • • 1d ago

CoQ10

7 Upvotes

Hey all
I am 27 and have pcos and endo. Has anyone tried coq10? I have heard good things about it for ttc. I have been ttc 1 year now with no luck yet. I heard its also good with energy levels which i am struggling with too. TIA


r/TTC_PCOS • • 1d ago

Progesterone 57nmol/L on blood test but no symptoms or BBT rise

1 Upvotes

Hey everyone, I've recently started my TTC journey and this month did a hormone panel out of curiosity as I also have a low libido. I've been doing OPKs as well as using the natural cycles app with wearable band to measure my BBT.

The first two months I had an obvious increase in BBT a few days after a positive OPK, followed by sore breast/nipples up until my period.

This month, I had a positive OPK on the 7th of October accompanied by ovulation pain. However, in the days since I have had no increase in BBT and no breast tenderness. I assumed I just hadn't actually ovulated. However, I then had the hormone blood test on the 12th October which said my progesterone was 57nmol/L. Everywhere I look says this means ovulation occurred. Now I'm confused! Has this happened to anyone else before?


r/TTC_PCOS • • 1d ago

Vent Was supposed to start medicated cycle tomorrow

1 Upvotes

Was supposed to start medicated cycle tomorrow but the fertility clinic called and said I had to come back Monday to bc my blood pressure was too high today. Has this happened to anyone ?

Today they said it was slightly elevated in the past but had never mentioned it to me?? Super frustrated. It could be just a 3 day delay, but they said the dr could also send me back to my PCP which could be another few months of delays before we can even start our FIRST medicated cycle (which we’ve been waiting 4.5 months to start) which has like a 10% success rate which just feels like nothing


r/TTC_PCOS • • 1d ago

Cystic Acne Remedies?

0 Upvotes

Hi everyone! I am looking for recommendations anyone has for cystic acne, especially in the jawline region.

I stopped taking spironolactone in December 2025, about two months before trying to conceive. While taking spiro I had virtually zero breakouts. We are still trying in October 2026, and my cystic acne has gotten worse with each cycle, and has flared up when I’ve needed to take progesterone to induce a period.

Has anyone found anything that has worked for them that is safe to use while TTC? I’ve tried the spot treatments, pimple patches, etc but I am really looking for something that’s not a topical. I have a dermatologist appointment but not until the end of November. Looking for suggestions to bring up with my derm at that appointment.

Thanks!!


r/TTC_PCOS • • 2d ago

Vent Friend complaining about pregnancy

29 Upvotes

I have been TTC for 3 years officially and unofficially like 6, my husband and I never used protection. We have 3 losses under our belts the most recent last week.

My best friend knows this and has a 9 month old and is in her second trimester with her second and shes been constantly complaining about her child and pregnancy. And I've been there for her but I'm just at a point right now where I cant.

She knows about the recent loss, I did gently tell her I mentally cant handle the venting right now and i a pretty sure she forgot.

I'm not like extremely mad at her and shes not a horrible person I'm just frustrated and really sad especially tracking this cycle to make sure the Letrozol worked and I get my period even if its later than usual. It also doesnt help that theres 3 women pregnant in my church and one of them was a few weeks ahead of me and I'm just.. not expecting my baby on mother day anymore and kinda wanna sleep and not wake up again.

Caveat: I am slightly depressed but won't ever do anything I love my husband and my life, I have a great support system so please dont read into the sleeping forever thing. Its just how I feel right now.


r/TTC_PCOS • • 1d ago

Discussion 2 day light period - any thoughts on impact for TTC?

1 Upvotes

I’m 36 TTC for 7 months with PMOS (acne/high androgens/high AFC). I was on birth control for a long time but both times I can recall being off it (for 6 months, and then again now for 11 months) my period has been a 2 day light bleed, with 3-5 days of brown spotting after. I’m confirmed to ovulate on my own each month. I’ve been followed by my RE for 3
TI letrozole, Ovidrel, and progesterone cycles. SIS is clear, tubes open, no polyps or fibroids.

The docs have never been able to comment really on the short period, does anyone have simialr experience and what has your doc attributed it to or what have you further investigated?


r/TTC_PCOS • • 1d ago

Seeking Success Birth control to help hormones and get pregnant in the future? Is it recommended?

1 Upvotes

In 2024 I got nexplanon. After 5 months of constant bleeding I removed it in February of 25 and decided I wanted to have a baby anyway. Got a positive test at the beginning of May.

I had a mc and ever since then I have had no success im wondering if I should try birth control again. I really hated nexplanon and I almost passed out getting it plucked out so i wouldnt do that just for funsies but probably the pill.

Has anyone had a doctor recommend this? Ive see a few posts here and there but not kuch follow up info.

I am scheduled to see them next week to discuss letrozole but if they continue pushing the discussion out like they have I might ask for birth control while I wait and maybe a few months of it will help? What do we think?


r/TTC_PCOS • • 2d ago

Sad So tired of not ovulating

9 Upvotes

Just a vent, I guess but always would love to hear other people success stories and vents as well.
My insurance doesn’t cover anything fertility, including letrazole.
My husband and I both agreed to wait at least another year and a half before committing to spending thousands on treatment.
I do ovulate 3-6 times a year (usually 4) and the lack of chances we get is devastating me.
I’m now on month 4 with only one ovulation, we timed everything perfect and still a no go.
Yet everyone around me is becoming a mom, even though I’m the one who has wanted this the most/longest.
I’m ready for my announcement, but I’m sure even when the day comes, I’m so traumatized by this process that I won’t be able to be truly happy until my baby is actually here.


r/TTC_PCOS • • 1d ago

Discussion Letrozole symptoms; peeing a lot

1 Upvotes

TW: early mc

Hi! My husband and I have been trying for 14 cycles now and have one 6 week miscarriage from cycle #1 to show for it. No luck for a year. My OB started me on Letrozole 5mg once a day (CD3-7.) I take my last dose tonight and was wondering how other people were feeling while on it? I know this has been asked before (and yes! I did speak to my doctor. I moved to be with my husband, so I don’t have a huge community where I am. It’s just nice to feel like I’m not alone) but I’m just seeing if there are new perspectives. I am peeing SO much on my first round of Letrozole.

I did have bloodwork and urine done, no issues there. What other symptoms did you guys have? I had breakthrough bleeding yesterday Earlier in the morning but it was gone by late morning, my OB does not seem to be concerned, I guess this is normal. I’ve had muscle pain in the same spot behind my knee and in my ankle since day 2 but it has not been progressively getting worse.

I don’t see my OB for ultrasound until CD 21, does this feel late for a monitored cycle? I can ovulate between cycle days 16-26 so I think it’s hard for them to guesstimate.

Sorry if this is kind of all over the place, we had to say goodbye to my kitty and I’ve been exhausted 🫠

TLDR:
Wondering what everyone’s symptoms were on Letrozole, talked with OB but trying to feel connected to community.

Edit: fixed TW


r/TTC_PCOS • • 2d ago

Cervical mucus, but no positive LH

3 Upvotes

My last cycle was the first time tracking, I had a classic cycle with cervical mucus(that I only checked the day after ovulation so I couldn’t know for sure) and a positive LH strip, and a good progesterone blood test a week later.

I get between 3 to 6 periods a year.

I have had egg white cervical mucus for the last six days, most notably the last three days I have found a lot. However, my LH is still nowhere near ovulating.

When I got my estrogen test tested, it came back completely normal a few months ago.

How long do you see cervical mucus before you ovulate


r/TTC_PCOS • • 2d ago

Advice Needed Letrozole and trigger shot

2 Upvotes

Hey, im new to the group, ill preface this by saying I dont have PCOS, my wife does and her and i are currently trying to conceive. We are working with Shady Grove Fertility in Eastern Pennsylvania, we love them so far but they are recommending timed intercourse with Letrozole and a trigger but the price per round is a thousand dollars which we don't have. We are looking into just seeing if she can do letrozole and no trigger as the biggest barrier with conception at this time is the lack of ovulation. Any advice and thought are greatly appreciated thank you!


r/TTC_PCOS • • 2d ago

Advice Needed First FET for IVF and clinic is insisting on Assisted Hatching

1 Upvotes

I'm really struggling with whether trying to argue with my fertility team about AH is worth it. I'm 27 (turning 28 in a few weeks) and am hoping to undergo my first round of FET soon. I went through 6 failed rounds of IUI.

My issue is that I received my treatment plan and assisted hatching is on it but I don't see it as necessary at the current time. I've done the research and read multiple studies and reports that indicate that there is no sufficient evidence on the performance of AH. Additionally, my insurance did deny coverage of AH because of this lack of evidence so I would be covering it out of pocket. Affording it isn't the issue but the out-of-pocket cost did play a factor in my research and decision.

With this being my first FET and my age, I don't believe its necessary but my clinic is being very insistent about it. I have 15 embryos and am willing to take the risk of failure.

The advice I need is, should I just give in and go along with the AH? What has been your experience with AH? Did you chose not to do AH and later regret that choice?


r/TTC_PCOS • • 2d ago

Advice Needed Advice needed- no ovulation

1 Upvotes

I started Ovasitol in July for high testosterone. I just got it rechecked and it had dropped to 44 from 65. I used Provera in September to induce a period and now currently cycle day 27 with no signs of ovulation. I’ve been on Ovasitol for 3 months. Should I continue? Add metformin? I’m just shocked I haven’t ovulated by now. Any advice?


r/TTC_PCOS • • 3d ago

Increased Progesterone

1 Upvotes

I just started 400mg of progesterone 4 days ago where I was at 200 previously but I never got my period after I finished it this last time. I’m now bleeding, not just spotting, and I still have the 6 days left to take it. Did this happen with anyone else to bleed like a period in the middle of the progesterone cycle?


r/TTC_PCOS • • 3d ago

Fluid Ultrasound

2 Upvotes

I recently had my HSG procedure done and the fertility clinic is recommending a follow up fluid ultrasound due to a potential (small) fibroid or polyp. Has anyone experienced this? My insurance doesn’t cover any fertility services and everything is so expensive. I sometimes wonder if these recommendations are money grabs…


r/TTC_PCOS • • 3d ago

Letrozole side effects

2 Upvotes

This is my first time trying letrozole. I took it 2.5mg days 3-7 on my cycle and had some nausea, headache and irritability but other then felt fine. Now I’m cycle day 11, 4 days after my last dose and I’m having the worst time. I feel dizzy like I’m spinning, nausea, anxiety and mild cramps and bloating. Has anymore else experienced this?


r/TTC_PCOS • • 3d ago

Letrozole 2 days only

1 Upvotes

Hello everyone,

My provider prescribed letrozole -3 pills 2.5mg (7.5mg total) for CD3 and 4. I haven’t really seen anyone talk about that course of letrozole anyone has a similar experience ?


r/TTC_PCOS • • 3d ago

Seeking Success Possible PCOS and TTC

2 Upvotes

This is my first time TTC. My husband and I have been trying for about 4 months, and I am starting to get discouraged. All of my doctors are saying "loose weight and stop stressing", but the stress part is almost impossible... In hopes to help with my insulin resistance, the doctors prescribe wegovy the pill and metformin. I haven't been formally diagnosed with PCOS, but have the insulin resistance.. My BMI is 33. I am only 23 and this is so mentally exhausting. Has anyone had anything similar? Any success? Any other advice? I am open to any an all...