I‘m sure a lot of people know this but I got to find out the hard way today. Nausea like crazy for a couple hours. It inhibits nicotine breakdown so your plasma levels increase and stay up longer, plus obviously more noradrenaline, adrenaline, and dopamine are released.

Used to be a smoker a few years ago (pack in a sitting sometimes), now 3 slims knocked me out.

I read people commenting about how they can "feel" serotonin when on SSRIs, as opposed to MAOIs, but no elaboration on what that feeling is.

I realise everyone is different and every experience will be different.

Can anyone explain to me how each of the neurotransmitters "feel" to them?

Is the feeling consistent across diagnoses?

In particular, I'm interested in differentiating between atypical depression with anxiety versus ADHD.

Hi I have been taking Nardil for just over a month (9 days on 45mg)

I am taking it for Social Anxiety and have yet to experience it's anti-anxiety effects

The last 5 days I have felt extra anxious even just when at home where social anxiety is not an issue because I am in my safe space, but the last 5 days even doing simple/basic things like taking the rubbish out, checking the mail box has me feeling extra anxious before doing these things (anticipatory anxiety), looking out the windows and making sure neighbours aren't outside so they don't see me etc.. I am even experiencing GAD, something that has never been an issue for me, only Social Anxiety. is this normal or should I be concerned?

A year ago I decided to try parnate for severe treatment resistant postnatal depression. I could cry thinking about how much it has helped me and wanted to share my story for others thinking of trying it (of course, YMMV). My depression was so severe I slept 14 hours, couldn’t even enjoy delicious food or a good tv show, cried daily for hours, and had constant thoughts that my new baby was better with a different mum. I did ECT, TMS, and tried countless medications. I was scared to try an MAOI for some reason and it took a few weeks of dizziness, nausea and random symptoms but after a few months I started enjoying things for the first time since my son was born. I could watch a tv show, sing, enjoy food. It brought back colour to my life. I was picturing my life being a dark hole forever and my son never knowing his fun weird silly mum. A year of parnate and I now sleep 9-10hrs, love going out for dinners again, sing and dance daily with my toddler, have been doing self care and made some mum friends. I was even singing alone in the car today enjoying the warm weather with the windows down. I never thought I’d find my way out but I did. Thank you parnate!

Is parnate as effective as nardil for social anxiety and blushing?

Also is it helpful for adhd with its stimulating effects?

Is parnate as effective as nardil for social anxiety and blushing?

Also is it helpful for adhd with its stimulating effects?

Please write which dose worked best for you and how you prefer to dose it throughout the day

I’ve tried every technique I read online and I just get an error message.

I’m worried my doctor won’t want to increase the dose of parnate without data on this.

Parnate

Is parnate as effective as nardil for social anxiety and blushing?

Also is it helpful for adhd with its stimulating effects?

Have only been on Nardil for 35 days and 7 days on 45mg and have yet to experience it's anti-anxiety benefits.

Once it hits, what does it feel like? Is the feeling similar to a benzo or more like propranolol? Or is the anti-anxiety feeling on a class of its own?

I got on 60mg of nardil after 3 days of 45mg. the first two weeks i felt really drunk , woozy, food tasted great, and i was giggling a lot like a drunk person .
week 3: fantastic mood and was able to walk through a store without anxiety. even though it didn’t touch a lot of my symptoms, these two parts of relief felt great. the best week i’ve had in years.
weeks 4-8: those benefits left. i decided to ride it out and hope maybe it’d come back but all i was left with was inorgasmia, constipation, and a bit of water weight gain
week 9: my doctor put me on 90mg. all i have felt was extremely tired. it’s been 4 days.

i don’t understand why the 60mg had me feeling something so briefly and then never worked. even if it didn’t touch 75% of my symptoms, the mood and ability to walk through a store without being anxious is what i miss. does this mean i shouldn’t even try 90mg since maybe the disappearance without reappearance of relief from 60mg is proof for some reason this medicine does not click within my body and mind? maybe because a history and dealing of neuroinflammation from lyme and mold and stuff? i just don’t get why week 3 happened and i got physical symptoms that have stayed if this medicine won’t work. i apologize for my ignorance. the science of MAOIS still confuse me!

I’ve heard some say it is slow process of working, but I’ve also seen others say when it comes you start feeling the effectiveness very suddenly.

Years of agoraphobia and too many failed meds, I'm considering nardil.

The road block is that I'm autistic and have a very limited diet and foods that are safe for me. I eat a lot of chicken nuggets and potato type foods that are frozen. And I eat a ton of boxed white cheddar shells, Mac n cheese etc. burgers with cheese and what I believe are safe breakfast foods and fruit that are of no concern. Is boxed Mac cheese and Kraft slices safe? I eat them daily and would like opinions as the literature isnt consistent.

I know my diet is terrible and I'm working on it lol.

Appreciate anyone who has has taken the time to read this and or offer insight. Take care <3

Parnate help

Hi all, for those who have taken Parnate, what has your experience compared to nardil? I suffer from extreme anxiety and social anxiety, depression, but I also have ADHD. I’ve heard this is more stimulating than Nardil, which is why it interests me to see if it could help ADHD, focus, executive function more than Nardil did.

I’ll get up in the morning and feel like death until I have a bowl of oats drowned in maple syrup or sugar and constantly crave sugar throughout the day.

Carbs or increased appetite aren’t really a a problem so I haven’t actually gained weight I’m just eating so much sugar which is so unhealthy

I genuinely can’t stop it through restraint and I’m not keen on GLP1s would anything else help??

Parnate

Parnate help

Hi all, for those who have taken Parnate, what has your experience compared to nardil? I’ve heard this is more stimulating than Nardil, which is why it interests me to see if it could help ADHD, focus, executive function more than Nardil did.

Is it okay to take stimulants everyday to help with intense drowsiness caused by MAOI's? Which stimulants are the best for this?

Been on an SSRI, 2 SNRIs, TCA, atypical. I don't really have anxiety or melancholy but prominent motivational apathy and anhedonia. Only drugs that briefly help my mood is caffeine and methylphenidate before crashing horribly. I can't try amphetamines or bupropion due to a seizure disorder, and I would like something that doesn't 'kick in' and 'come down' daily.

Would an MAOI (or anything else) provide a subtle but more sustained pro-motivational effect like a stimulant does?

I am confused. For Social Anxiety some places online say 45mg, others say 60mg

Have been on 45mg for 6 days (On Nardil for 34 days in total) and I have not seen any Social Anxiety symptoms reduction yet, only side effects E.g severe hypersomnia, increased appetite and weakness/fatigue and some insomnia

When will this SA Gold Standard medication start working?

I have a really bad cough / cold and I took some Dayquil to try to feel better. It says you should absolutely never take it if you are taking a MAOI. I take 30mg of parnate.

Now online is telling me I will get a hypertensive crisis. I am on hold with poison control. I also take 150mg of Wellbutrin but have never had serotonin syndrome.

I started over a month ago at 45mg, and then increased to 60mg a little over 2 weeks ago. Do I still need to wait longer to feel something at 60mg? Or do I just need to increase the dose if it’s not working yet?

Hi all, for those who have taken Parnate, what has your experience been? I suffer from extreme anxiety and social anxiety, depression, but I also have ADHD. Nardil had helped my anxiety as well as chronic blushing. for those who struggle with blushing when anxious may understand. for those on Parnate how would you say it is for your anxiety and social anxiety and blushing? I’ve heard this is more stimulating than Nardil, which is why it interests me to see if it could help ADHD, focus, executive function more than Nardil did.