I got on 60mg of nardil after 3 days of 45mg. the first two weeks i felt really drunk , woozy, food tasted great, and i was giggling a lot like a drunk person .
week 3: fantastic mood and was able to walk through a store without anxiety. even though it didn’t touch a lot of my symptoms, these two parts of relief felt great. the best week i’ve had in years.
weeks 4-8: those benefits left. i decided to ride it out and hope maybe it’d come back but all i was left with was inorgasmia, constipation, and a bit of water weight gain
week 9: my doctor put me on 90mg. all i have felt was extremely tired. it’s been 4 days.

i don’t understand why the 60mg had me feeling something so briefly and then never worked. even if it didn’t touch 75% of my symptoms, the mood and ability to walk through a store without being anxious is what i miss. does this mean i shouldn’t even try 90mg since maybe the disappearance without reappearance of relief from 60mg is proof for some reason this medicine does not click within my body and mind? maybe because a history and dealing of neuroinflammation from lyme and mold and stuff? i just don’t get why week 3 happened and i got physical symptoms that have stayed if this medicine won’t work. i apologize for my ignorance. the science of MAOIS still confuse me!

Parnate help

Hi all, for those who have taken Parnate, what has your experience compared to nardil? I suffer from extreme anxiety and social anxiety, depression, but I also have ADHD. I’ve heard this is more stimulating than Nardil, which is why it interests me to see if it could help ADHD, focus, executive function more than Nardil did.

Years of agoraphobia and too many failed meds, I'm considering nardil.

The road block is that I'm autistic and have a very limited diet and foods that are safe for me. I eat a lot of chicken nuggets and potato type foods that are frozen. And I eat a ton of boxed white cheddar shells, Mac n cheese etc. burgers with cheese and what I believe are safe breakfast foods and fruit that are of no concern. Is boxed Mac cheese and Kraft slices safe? I eat them daily and would like opinions as the literature isnt consistent.

I know my diet is terrible and I'm working on it lol.

Appreciate anyone who has has taken the time to read this and or offer insight. Take care <3

I’ve heard some say it is slow process of working, but I’ve also seen others say when it comes you start feeling the effectiveness very suddenly.

I’ll get up in the morning and feel like death until I have a bowl of oats drowned in maple syrup or sugar and constantly crave sugar throughout the day.

Carbs or increased appetite aren’t really a a problem so I haven’t actually gained weight I’m just eating so much sugar which is so unhealthy

I genuinely can’t stop it through restraint and I’m not keen on GLP1s would anything else help??

Parnate

Parnate help

Hi all, for those who have taken Parnate, what has your experience compared to nardil? I’ve heard this is more stimulating than Nardil, which is why it interests me to see if it could help ADHD, focus, executive function more than Nardil did.

Is it okay to take stimulants everyday to help with intense drowsiness caused by MAOI's? Which stimulants are the best for this?

Been on an SSRI, 2 SNRIs, TCA, atypical. I don't really have anxiety or melancholy but prominent motivational apathy and anhedonia. Only drugs that briefly help my mood is caffeine and methylphenidate before crashing horribly. I can't try amphetamines or bupropion due to a seizure disorder, and I would like something that doesn't 'kick in' and 'come down' daily.

Would an MAOI (or anything else) provide a subtle but more sustained pro-motivational effect like a stimulant does?

I am confused. For Social Anxiety some places online say 45mg, others say 60mg

Have been on 45mg for 6 days (On Nardil for 34 days in total) and I have not seen any Social Anxiety symptoms reduction yet, only side effects E.g severe hypersomnia, increased appetite and weakness/fatigue and some insomnia

When will this SA Gold Standard medication start working?

I have a really bad cough / cold and I took some Dayquil to try to feel better. It says you should absolutely never take it if you are taking a MAOI. I take 30mg of parnate.

Now online is telling me I will get a hypertensive crisis. I am on hold with poison control. I also take 150mg of Wellbutrin but have never had serotonin syndrome.

Hi all, for those who have taken Parnate, what has your experience been? I suffer from extreme anxiety and social anxiety, depression, but I also have ADHD. Nardil had helped my anxiety as well as chronic blushing. for those who struggle with blushing when anxious may understand. for those on Parnate how would you say it is for your anxiety and social anxiety and blushing? I’ve heard this is more stimulating than Nardil, which is why it interests me to see if it could help ADHD, focus, executive function more than Nardil did.

I started over a month ago at 45mg, and then increased to 60mg a little over 2 weeks ago. Do I still need to wait longer to feel something at 60mg? Or do I just need to increase the dose if it’s not working yet?

Hey everyone, longtime Nardil patient here and I’ve ran into my first roadblock with MAOIs. I’m not finding anything that can be used for nausea, only no therapeutic doses of ginger (soda/tea). I’ve read that while Zofran may be an option, it is not fully understood whether ST can accumulate and cause ST syndrome. AI claims it is done so with antagonism of one ST receptor, forcing an accumulation of ST in the brain. Has anyone safely used an alternative medication for nausea while on a MAOI?

had to quit it due to summer heat in august. now it's cold outside and depression creeps in

this drug has been my best friend last year, even with side effects. i can actually feel it helping me even tho it's subtle

and i would vote for Pirlindole post flair (it should be baby blue color. pills are just white)

i also take Noopept, Coq10, palmitoylethanolamide and a shit ton of caffeine. fell in love with Red Bulls recently (sorry body)

let's hope it will help 🤍

We all know weight loss is hard on Nardil. Those who have succeeded, or at least lost a decent amount of weight. Did it just take a lot longer than normal and you had to grind? How much harder does Nardil make it? Surely eating in a decent deficit for long enough, you lose weight? Thanks to anyone who responds 😄

I’m asking my psychiatrist for it. He prescribed me Segelegine but my insurance didn’t cover it. I tried Wellbutrin, Zoloft, and many other ssris and snris and I’m 19. Zoloft helped some, but after a while I felt depressed again.

Wellbutrin just made me a really anxious. What do maois feel like? No antidepressant I’ve tried gave me any happiness or hope for the future. It’s more of a complete content and lazy feeling. No emotions or anything to look forward to. No motivation just flat.

I fast tapered off my Effexor in February (too fast) and I’ve been brain fried since then I can’t think, my depression has been getting worse slowly and my accutane gave me horrible exhaustion and I’ve been off it for 4

Hey Ive been taking atomoxine for my ADHD and it's been helping but not really for mood and motivation, I bedrot all day watching anime and I'm thinking of adding parnate but not sure if psychiatrist would allow me. So would it be better to see another psychiatrist?

Ive been taking effexor since April for my social anxiety and it helped reduced my mental social anxiety a bit but I still stay in my bed all the time not sure why I thought It was ADHD so I complained about it to my psychiatrist and he prescribed atomoxine I'm like 3 weeks 40mg and 2 weeks and 3 days on 60mg (moved up) and it helped quiet my mind a bit more but I still feel the same I still don't have motivation to do activities and do my learning. I'm considering switching to nardil but I don't know if that'll help. Sometimes my mood goes up which makes me motivated to do stuff but it's pretty temporary and lasts like 1 minute before falling back

No matter how poorly you sleep, for several days in a row, you still lose nothing of cognition

For the people who have tried both, which of the medication helped you more with anxiety/social anxiety?

I've been taking trivon (tranylcypromine from INTAS) for the past 2 months. On 10mg for the first 10 days and 20mg for the rest. This is the first time I've reacted this strongly to an antidepressant. After taking it in the morning I would feel incredibly tired for the rest of the day. Sometimes just standing up makes me see blotches and random color patches, like a dying CMOS on a camera struggling to produce a coherent image. So far what I've been experiencing has been the complete opposite of what I'm expecting. It's the opposite of stimulating, and it makes doing everyday tasks very hard.

Antidepressants generally don't give me much trouble. I've been on all 5 SSRIs and 2 SNRIs and quit all of them cold turkey without feeling much. This trivon stuff though is something else, I am getting more reaction out of this than the 7 SSRI/SNRIs I have taken combined. Right now I'm more inclined to believe it's the manufacturer rather than tranylcypromine cuz there is no way an antidepressant makes you feel like this.

hello? alive?

if none of you are going to ever check in, make me a mod.

at least I exercise a modicum of attention to the people asking questions here.

edit: people keep citing vivid and Technical as if this was personal. it's not, I am acquainted with both of them and I like them and know they are way more knowledgeable than I am.

there are like three other mods that are never here.

don't make assumptions. and also relax.

and feel free to check my history if you're wondering how much I've contributed to this sub over the years. including generosity towards anyone I've responded to, whether they're facing a common issue that could easily be solved via a sub search, or an extremely challenging hurdle.

edit 2: also, keep downvoting me and don't say anything, because that's useful. if you leave even one downvote, show your cowardly face and go over what you've done for this subreddit.