r/Effexor • • 15h ago

General Question Anyone had abnormal liver blood results on high dose?

3 Upvotes

I've been on 300mg a while now but recently had blood tests done and my liver function is abnormal. I am having other follow up tests to see what could be wrong. However I am wondering if anyone has experienced liver problems on a high dose of venlafaxine? I'm considering discussing with my GP about


r/Effexor • • 13h ago

Side effect 3rd times a charm - GAD, Panic, DPDR

2 Upvotes

So my anxiety and panic like to flare up from time to time so knowing that I’ve been on Effexor twice before (2018 and 2025) and have had great success with it - i went back on it for a 3rd time.

its funny cause the first i took it, no start up side effects at all. the 2nd time, I had to go the hospital 3 times because of how bad the anxiety, panic attacks, etc. got. Luckily this time around, i knew that the side effects would come again.

Now on day 18 (started at 75mg) and that was hell in the beginning and now on day 6 of jumping to 150mg. unfortunately I'm feeling like a zombie right now and the morning anxiety is dreadful as well as the afternoon dread and anxiety.

How do y’all cope during the start-up period?

I was given bridge meds but I only take them if it gets out of hand and i can't function (unfortunately right now, It's been happening a lot)

anyways stay strong everyone 💪

I've gotten off the medication twice so if anyone needs help, feel free to ask away.


r/Effexor • • 23h ago

Beginning Effexor Is it worth it for anxiety only?

2 Upvotes

I (29M) have been prescribed venlafaxine (effexor) for anxiety 2 days ago. I have struggled with anxiety and depression all my life but have been taking bupropion and that helped my depression a lot (now stopped it a couple weeks ago and depression hasnt come back) but didnt do that much for anxiety. I really want to get help with anxiety but I am also generally feeling quite okay and able to function.

My psychiatrist suggested me to try Venlafaxine. She said this drug is something i can just take for a short time, but now reading online I see a lot of horrible stories, especially with withdrawals and getting worried.

Wanted to ask do you guys feel it was worth it for you? Did anyone take it mainly for anxiety? Is it something you would only take as a last resort?


r/Effexor • • 48m ago

Tapering Tapering off. Is this too fast?

• Upvotes

Hi all, I’m finally trying to get off this drug after accepting it isn’t helping me and may be the cause of hypomanic episodes I had this year after the dosage was increased to 225mg.

I’ve been back down to 112.5mg for a while when I finally called my doctor’s office asking for help tapering off it. My doctor has been out so I was given instructions from another telling me to begin taking 75mg for a week, followed by 37.5mg until my appt with my regular doctor at the end of this month.

I thought I would be okay since I somehow saw no difference between 225 and 112.5 but this has been a bit awful. The physical symptoms are one thing, but my mood has tanked badly and I’ve been struggling with not the best thoughts. But for right now I’m lucid enough to realize it’s from the withdrawal.

I am desperate to get off of this so I’m gonna tough it out, but could it be that I’m being tapered off too quickly, or is this normal? Thanks


r/Effexor • • 8h ago

Beginning Effexor 1.5 weeks in - does tiredness go away?

1 Upvotes

I’m about 1.5 weeks in on 37.5 mg. My mood, irritability and anxiety surprisingly all feel slightly better. It’s modest but feels good. However, I am TIRED. Napping and skipping my work outs. Does this go away?

Thanks so much - any insight is greatly appreciated! 🙏💕


r/Effexor • • 8h ago

Quitting Withdrawal after only 6 days?

1 Upvotes

Hi all - I took Effexor XL 37.5mg for 6 days and didn’t feel too many early side effects, but discontinued when I noticed sexual dysfunction, as I have a history of sexual dysfunction with SSRIs and I’m not willing to go down that path again. However, on day 2 after quitting I feel extremely lethargic - unable to go into work, unable to stay awake for more than a few hours, feeling like I’m trapped in amber, feeling like a zombie. I really didn’t think the withdrawal would be so noticeable after only 6 days on a low dose.

Can anyone advise what I should expect going forward? How long will this take to get through? Do I need to do a slower taper? I saw posts about opening the capsules and removing some of the beads on here, but my prescriber hadn’t mentioned any of that, and again I didn’t expect to have this kind of issue after such a short trial.


r/Effexor • • 9h ago

Withdrawal Is it normal to feel depressed and sad after a 75 mg drop to a 37.5?

1 Upvotes

It has been 17 days since I dropped it. Is this still withdrawal or is this just how I normally am/will be?


r/Effexor • • 10h ago

Quitting Switching from Venlafaxine to Bupropion

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1 Upvotes

r/Effexor • • 10h ago

Withdrawal From Venlafaxine to Bupropion

1 Upvotes

Hello everybody! I am diagnosed with Bpd, Depression and Anxiety. Lately i have been feeling bad, very depressed, anhedonic. I also lost my job and didn’t help that. I have been splitting on my boyfriend and I feel very bad for him because he doesn’t deserve this. But somehow I try to manage everything an go on.

Since 2 days ago, I was taking 2,5 mg olanzapine at night, and 75 mg Venlafaxine and 10 mg Escitalopram in the morning. My psychiatrist chaged a bit my combo.

Yesterday, I started taking 5mg Olanzapine and 300 mg Gabapentine, and in the morning 20 mg Escitalopram , and 150 mg Bupropion. For now I feel pretty stable and had a decent mood.

I read that Venlafaxine gives you a pretty rough withdrawal, so I am curious to know if anyone switched from Venlafaxine to Bupropione and how did it feel. Also, if you have any recommendations or a good word to say, would be very helpful.

In the last months I tried many meds and they didn’t work so good on me so I really hope this time, this combo of medication will work on me.

Thanks, and have a great evening! 🫶🏼


r/Effexor • • 11h ago

General Question Vecka 8 på Venlafaxin (Effexor) – Svår ångest, gråtanfall och fortfarande ingen lindring från depression. Blir det bättre?

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1 Upvotes

r/Effexor • • 11h ago

Concern Brain zaps

1 Upvotes

I've been on venlafaxine for about two months now, major depression/ generalized anxiety

I take it at the same time every day and it just seems like sometimes I digest too quickly? Or something and I start getting the brain zaps and confusion and dizziness and erratic emotions, I'm really not sure what's happening but when I bring it up to the doctor they don't really know either so I'm taking it out of the capsule and putting it in applesauce at her recommendation. That worked for a few days and then one day I started feeling extra dizzy and after a few more hours I was having the brain zaps again. What's going on, is there any way this could be related to eating habits? If anyone has some insight that would be so very greatly appreciated 👍


r/Effexor • • 12h ago

Tapering Hyperbolic tapering - is it better?

1 Upvotes

Been working on coming down from 225mg and was at 150mg for a while, so decided to go down again. Just gone from 150 - 112.5mg. Smartly, I decided to do this as I've started a masters. Holy crap. I forgot how bad it was... like the brain zaps, cognitive symptoms (I feel like a ghost), and the flu-like symptoms. I'm not doing 'hyperbolic tapering', tbh I only heard of the concept through this sub-reddit, but is it worth it?? I don't know if it's something I should consider raising with my psychiatrist. I know it's supposed to get worse the lower you get, so I am a little terrified...


r/Effexor • • 14h ago

Beginning Effexor Mirtazapine withdrawal

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1 Upvotes

r/Effexor • • 15h ago

Side effect Day 6 total insomnia and racing head

1 Upvotes

So last night I was literally dropping by 7pm but when I went to bed at 10.30 thoughts were on a loop and total insomnia all night….

This is a bit of a roller coaster, was this similar for others then settles?

I’ve dragged myself out of bed at 2pm!!!!

😬


r/Effexor • • 18h ago

General Question Acid reflux and anti depressants

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1 Upvotes

r/Effexor • • 20h ago

Concern Increase dose to 150

0 Upvotes

Hi I am at 112mg and I still feel anxious when I get stressed. I can feel it so intense on my chest. I was on 150 before that made me super numb. I feel stuck can some help me.


r/Effexor • • 9h ago

Side effect Smoked THC cart for the first time on Effexor. Sick the morning after.

0 Upvotes

I was about 45-50 days THC free. I quit before so I can start on a new depression medication. Smoked last night and I have been throwing up all morning and afternoon. Throw up 3 times. This has never happened. As

I am not new to THC carts or taking a extended t break and coming back no problem. I'm not sure if Effexor has anything to do with it or not. I'm not sure if it changed my system or were I longer can handle high thc content like I used to before.

Today is day 9 of taking Effexor. Went from 37.5 mg for the first week to 75 mg I've been taking 75 mg for the last three -four days and I've been fine.