r/5MeODMT • • Jan 14 '26

5-MeO-DMT FREQUENTLY ASKED QUESTIONS (WIP)

41 Upvotes

5-MeO-DMT FREQUENTLY ASKED QUESTIONS

Disclaimer:
The following FAQ is intended for educational and harm-reduction purposes only. It does not constitute medical advice, diagnosis, or treatment. 5-MeO-DMT is a powerful psychoactive substance that should only be used with appropriate screening, supervision, and integration support. Always consult a qualified healthcare provider before making decisions related to mental or physical health.

Subreddit Questions

What is the purpose of the r/5MeODMT subreddit?
The subreddit is a community for sharing experiences, research, safety information, and harm-reduction practices related to 5-MeO-DMT.

Why does r/5MeODMT emphasize caution over promotion?
The community prioritizes safety, education, and harm reduction rather than encouragement of use.

Is 5-MeO-DMT suitable for casual or recreational use?
The subreddit generally discourages casual use due to the substance’s intensity and risks.

Why does the community often emphasize synthetic forms?
Synthetic versions allow for more predictable purity and avoid ethical or ecological harm.

Does r/5MeODMT allow sourcing or buying discussions?
No. The subreddit follows Reddit’s rules and does not allow sourcing, selling, or buying of illegal substances.

Are there legal concerns discussed in the subreddit?
Yes. Legal status varies by country and region, and users are encouraged to research local laws before engaging with the substance.

GENERAL QUESTIONS

What is 5-MeO-DMT?
5-MeO-DMT (5-Methoxy-N,N-Dimethyltryptamine) is a naturally occurring substance of the tryptamine class.  It is structurally related to DMT and 5-HO-DMT (bufotenine) and is a powerful, fast-acting psychedelic compound known for producing intense, non-visual, and often ego-dissolving experiences.

Is 5-MeO-DMT dangerous?
5-MeO-DMT can be dangerous under certain circumstances. Risk factors include contraindicated medications (particularly SSRIs or MAOIs), preexisting cardiovascular disease, and a history of severe mental health conditions. Additional dangers may involve asphyxiation from purging, physical injury during uncontrolled movements, or lack of supervision. To minimize risks, always work with an experienced, trained 5-MeO-DMT facilitator who conducts proper screening and safety protocols.

How is the psychedelic experience with 5-MeO-DMT different from N,N-DMT?
Although chemically related, 5-MeO-DMT and N,N-DMT produce distinctly different experiences. N,N-DMT tends to be highly visual, often involving complex geometric imagery and encounters with entities, while the user’s sense of self remains intact. 5-MeO-DMT is typically less visual and characterized instead by ego dissolution — the temporary loss of personal identity and merging with a non-dual or unified state of consciousness.

Is 5-MeO-DMT going to fix me?
5-MeO-DMT is not a cure or a quick fix. It can act as a catalyst for personal insight and transformation, but lasting benefits require active integration — the process of applying insights from the experience into everyday life. Meaningful change arises from continued inner work, not from the experience alone.

Is it possible not to come back from a 5-MeO-DMT experience?
With proper medical and psychological screening, the risk of not “returning” is extremely low. However, individuals with preexisting psychiatric disorders or those who use 5-MeO-DMT without proper support may experience psychological destabilization, including psychosis. In rare cases, physical harm or death can result from unsafe environments or improper dosing. Responsible facilitation and screening are essential.

Can I have a bad trip on 5-MeO-DMT?
Yes. Challenging experiences can occur and are often viewed as opportunities for emotional processing and growth. Fear, resistance, or loss of control may arise during ego dissolution. Adequate preparation and skilled facilitation reduce the likelihood and intensity of these difficulties. If a challenging experience occurs, the best approach is to relax, surrender, and allow the process to unfold.

Is 5-MeO-DMT right for everybody?
No. 5-MeO-DMT is a powerful substance that is not suitable for everyone. Individuals with unstable mental health, cardiovascular disease, or those currently taking contraindicated medications should not participate. Even for healthy individuals, psychological readiness and timing are critical. Pre-screening by an experienced facilitator is strongly recommended.

Is it safe to use 5-MeO-DMT while taking SSRIs?
Combining SSRIs with 5-MeO-DMT can be dangerous due to potential serotonergic toxicity and unpredictable interactions. Due to 5-MeO-DMT having additional mechanisms of action such as reuptake inhibition of neurotransmitters such as serotonin, noradrenaline and dopamine are also thought to be involved to an extent. This can result in 5-MeO-DMT becoming dangerously toxic when combined with MAOIs, RIMAs, SSRIs, stimulants or any substance which acts as a releasing agent or reuptake inhibitor of monoamine neurotransmitters.

What is the difference between Incilius Alvarius secretion and synthetic 5-MeO-DMT (“The Pure Molecule”)?
The secretion from the Incilius Alvarius toad formerly known as Bufo Alvarius and known as the Sonoran Desert toad or as the Colorado River Toad contains 5-MeO-DMT alongside numerous other tryptamines and alkaloids such as 5-MeO-NMT and bufotenin. It is collected from the toad’s parotoid glands, dried, and vaporized. Synthetic 5-MeO-DMT — known as “The Pure Molecule” — is produced in laboratories as a white, gold and even brown crystalline powder and vaporized similarly. Most users report little difference in subjective experience. From an ethical and ecological standpoint, synthetic 5-MeO-DMT is preferred to avoid harm to toad populations.

What forms of 5-MeO-DMT are there, how are they administered.

  • Vaporization (inhaling vaporized freebase or toad secretion) This is most common route with an intense and rapid onset (10-20 sec)
  • Insufflation (intranasal, or snorting freebase) This way provides longer onset 15 mins for effects to begin and 1-5min for the come up, with the drawback of nose burning.
  • Intranasal Mist (snorted or inhaled salt solution) This way provides longer onset 15 mins for effects to begin and 1-5min for the come up.
  • Intramuscular Administration (IM, muscle injection of salt solution) with onset times slightly longer than that of insufflation.
  • Rectal Administration (plugging, boofing salt solution or powder): This way provides the longest onset (3-10min for direct solution insertion, 10-20 min for capsuled insertion).

What are standard dosing recommendations.

Tl;Dr: (assuming vaporized) 2-3mg of freebase or 15mg of Bufo and go from there

The question "What amount should I use to achieve a given state?" is often asked. And the real (and complicated) answer is: nobody knows - what the answer is for the specific case - aka. - you.

There are too many variables to be able to reliably know what this number for a given person is - the smoking technique, the apparatus used, the material (freebase/bufo/HCL/Oxylate) used, the application route (smoked/IM/mucous), and about 5 other things, all affect the experience non-linearly. And the final variable that affects everything MORE than all of the above combined is - the internal constitution of the person undergoing the experience. We're all different. Full-stop.

It is a plain fact - that some folks need 4x the material than others do - and some need 1/2 as much - to reach a 'peak' experience. We humans don't quite know why this is so - but it is a clear documented fact. Sure, there's likely a 'bell curve' distribution of tolerance - and the majority DOES skew towards the mean - but the problem is - starting out - nobody knows where THEY are at. And the 'lightweights' and the 'hardheads' are not small singe-digit percentages of the population.

An individual's tolerance to other Psychedelics absolutely does not correlate with 5-MeO-DMT tolerance (likely because it is the only common-enough psychedelic that primarily targets the 5-HT1A receptor, unlike practically all others which all primarily target the 5-HT2A receptor). It's fundamentally 'a different thing' for your body-system.

The way that 'shamans' deal with this 'nobody can tell' issue is to give EVERYONE an extremely-large-dose - to make sure to get everyone of any tolerance 'there.' It is the strong belief of this space that this type of an approach results in a large amount of unnecessary harm - for folks who are taken too-far-out - to a situation where no memory remains, no lessons are learned, and a shocked profoundly destabilized entity reassembles on the other side of the so-called 'whiteout.' This going 'too far' for somebody's 'first time' - likely results in the majority of the negative and damaging experiences that folk have with this substance.

With this space being primarily focused on promoting safety and conscientious use of the sacrament - we are presented with a hard choice - give the 'rough numbers' that will result in unexpected-unplanned-very-potentially-difficult experiences for some large non-zero percentage of the readers - or to encourage a gradual "learn how YOU respond to the medicine" approach.

We chose to do the latter. Recommendation is to start low - increase gradually - and engage in this in the company of others for safety. Starting with 2-3mg of freebase or 15mg of Bufo - starts one off in a safe space that allows for clarity and information to be gained - about your desires on where to go further.  

What are reactivations, and why do they happen?
Reactivations are spontaneous recurrences of sensations or consciousness states from the 5-MeO-DMT experience that arise after the main session. They occur in roughly 10–15% of participants, often within the first few days, particularly during sleep. Their cause is not fully understood; possibilities include residual energetic or neurological processing. While typically benign, reactivations can be distressing if intense or prolonged. Support from an integration specialist can help manage them safely.

Is it normal to not remember my 5-MeO-DMT experience?
Yes. Memory loss is common due to the nature of ego dissolution and the absence of a self-reflective observer during peak effects. Even without explicit memories, participants often report lasting emotional or cognitive changes. Integration work helps translate these subtle shifts into lasting growth.

If I keep doing 5-MeO-DMT frequently, will my ego disappear?
No. Frequent use without integration may strengthen the ego’s defense mechanisms, leading to what is sometimes called “spiritual bypassing” or “ego inflation.” Sustainable transformation requires reflection and integration between experiences. Repeated use without integration can undermine potential benefits.

Is it normal to purge (vomit) during a 5-MeO-DMT experience?
Yes, though it occurs in only about 10–15% of participants, and full purging is rarer (1–5%). Purging may represent both physical and energetic release. Facilitators should have safety measures in place, including purge buckets and knowledge of recovery positioning.

What is the difference between taking a large dose versus a small dose of 5-MeO-DMT?
Larger doses do not necessarily equate to deeper experiences. Depth is determined more by one’s ability to surrender. Higher doses often induce full ego dissolution, while smaller doses can support targeted therapeutic or emotional work. The appropriate dose depends on intention, experience, and facilitator guidance.

Is licking toads a psychedelic practice?
No. Licking toads is dangerous and can be fatal. The Bufo Alvarius secretion must be properly collected and vaporized; direct contact with the toad’s toxins poses severe health risks and has no psychedelic benefit.

Are toads at risk due to the popularity of 5-MeO-DMT?
Yes. Increased demand for Bufo Alvarius secretion has contributed to ecological harm, overharvesting, and disease spread. The use of synthetic 5-MeO-DMT is strongly recommended for ethical and conservation reasons.

How often should I use 5-MeO-DMT?
There is no set frequency. Individuals should only engage with 5-MeO-DMT once prior experiences are fully integrated and there is a grounded, internal motivation to continue. Frequent use without integration can lead to psychological imbalance and ego reinforcement.

EXPERIENCE QUESTIONS

How do I prepare for my 5-MeO-DMT experience?
Preparation promotes safety and psychological readiness. In the week before the session, maintain a clean diet, avoid alcohol and drugs, and engage in grounding practices such as meditation or journaling. Clarify your intentions and organize post-session downtime for integration.

How can preparation make a difference in my 5-MeO-DMT experience?
Preparation directly impacts one’s ability to surrender and navigate the experience. Understanding what to expect and developing self-regulation tools reduce anxiety and resistance, increasing the likelihood of a safe and meaningful outcome.

Is it normal for 5-MeO-DMT to bring up trauma?
Yes. 5-MeO-DMT may surface unresolved trauma for processing and release. This can be emotionally challenging but often facilitates deep healing. Support from an experienced integration specialist can help ensure that this process remains safe and productive.

Why is it important to integrate after 5-MeO-DMT?
Integration is how insights become lasting change. Without it, the experience may fade quickly, and old behaviors can resurface. Integration practices — reflection, therapy, and mindful action — consolidate the benefits of the session.

Is it normal to feel like my life is crumbling during my integration period?
Yes. Post-session shifts in perception can cause major life changes, including altered relationships or priorities. This disorientation is part of the reorganization process. With support and time, it often gives way to greater clarity and authenticity.

How can I prepare for my integration after the 5-MeO-DMT experience?
Plan for several days of rest and reflection after your session. Focus on grounding activities such as meditation, nature, journaling, and self-care. Limit exposure to stressful environments or media. Protect your energy and seek supportive people. Integration specialists can offer additional tools for processing insights and stabilizing change.

Where can I get support for integrating the experience?
Begin by contacting your facilitator for follow-up. If additional help is needed, work with a 5-MeO-DMT integration specialist or therapist familiar with psychedelic integration. Professional guidance can help manage difficult emotions, deepen insights, and ensure safety.

How long should integration take?
Integration has no fixed timeline. It can unfold over days, months, or years depending on the individual and the depth of their experience. Patience and consistent self-reflection are essential.

FACILITATION QUESTIONS

How do I choose a 5-MeO-DMT facilitator?
Selecting a qualified, ethical facilitator is essential for safety and outcome quality. Research their background, training, and protocols. Meet with them to discuss preparation, dosing, and integration. Choose someone who fosters trust and psychological safety, as this is key to fully surrendering to the experience.

What are some red flags to be aware of when choosing a facilitator?

  • Serious allegations: Avoid facilitators with reports of deaths, sexual misconduct, or malpractice.
  • Reckless behavior: Dangerous actions such as restraining participants, pouring water into mouths, or giving unrequested substances.
  • Unnecessary interference: Facilitators should not direct or control the participant’s process unless for safety.
  • Psychological imprinting: Avoid those seeking emotional validation or praise from participants post-session.
  • Lack of safety protocols: Red flags include no medical screening, no assistants, or unsafe environments.
  • Profit-driven marketing: Oversized groups, excessive fees, or posting participant media for promotion.
  • Poor preparation/integration: Inadequate education, screening, or follow-up support.
  • Large groups (>15): Reduce quality of care and safety.
  • “Certification chasers”: Facilitators serving multiple psychedelics without deep expertise.
  • Self-proclaimed shamans: 5-MeO-DMT has no indigenous shamanic lineage.
  • Messiah complexes: Facilitators showing spiritual narcissism or superiority are high-risk.

What are some questions I should ask my facilitator?

  • What formal training and experience do you have?
  • How do you prepare participants?
  • Do you have first aid or emergency training?
  • What integration resources do you offer?
  • What is your facilitation style, and why?
  • Why do you work with 5-MeO-DMT?
  • What safety measures are in place?
  • How is the medicine sourced?
  • How long have you been facilitating, and how many sessions have you led?

What are the different types of 5-MeO-DMT ceremonies? What are the pros and cons?

  • Private one-off ceremony: One session with a single participant.
    • Pros: Personalized attention, flexible scheduling.
    • Cons: Limited preparation and integration support.
  • Group one-off ceremony: Multiple participants in a single session.
    • Pros: Accessible and social.
    • Cons: Reduced individual care; minimal integration; unsafe above 15 people.
  • Group retreat: Multiple ceremonies over several days with a small group.
    • Pros: Built-in integration time, peer support.
    • Cons: Less personal attention in larger groups.
  • Private retreat: Multiple sessions with one participant over several days.
    • Pros: Deeply individualized support, flexible pacing.
    • Cons: Higher cost.

What is the 5-MeO-DMT experience like as described by r/5MeODMT mod u/Shaman-Shakers**?**

5-MeO-DMT at full dose is a death simulation experientially, there is no other compound that so reliably annihilates the ego/self so completely as 5MEODMT.

5MEO is in no way comparable to any other experience one will have had and any previous experience with psychedelics though helpful will not help to conceptualize what is experienced on 5MEO.

5MEO is 100% an energetic experience, when working with 5MEO you are working with your energetic system which isn't common knowledge, it isn't well documented and then many are not willing to entertain the idea that they have an energetic system sometimes referred to as Chakra, Chi and Prana.

5MEO seems to have a specific task it performs, it does this one thing, and it does only this one thing and that is an equalization, recalibration, resetting or factory defaulting (however you like to box it) of one's energetic system, chakras, aura, chi, prana (again however you box it). That's it, that's all it is fundamentally doing.

Experientially i.e., what one experiences as this process unfolds can vary widely based on dosage and the unique individuals' energetic states and psychology.

We will cover the "full release" or "breakthrough" dosing experience as it is most sought after.

In order for 5 to provide the "full tension release" as it's referred to often in medical journals, the compound must work through your energy state as it is, if you have held unresolved, unprocessed emotional energies (trauma) this is worked through first and it can be quick or a multiple experience process depending on depth of trauma, length of time it is been held etc., also depends on one's ability to remain equanimous and fully surrender to what is happening. Those seeking trauma healing often have difficultly here.

As 5works through your energies one experiences in real time ego dissolution or ego death, 5 requires the "default mode network" of your Nero circuitry to be fully circumvented to complete its work. For an initiate this is the experience of complete and total annihilation of the egoic structure or in other words an experiential death. One will experience themselves dissolving into nonexistence as the self.

Once fully dissolved one will have reached the peak of the experience and at this point there is no self, no linear thought, no access to memories or any other "mind" or ego related neuro functions. One is fully absorbed into pure conscious awareness, oceanic boundlessness, a sense of being all things and nothing at the same time often occur here. The subject object relationship no longer exists, and one is experiencing pure subjectivity. Also, many discover their true nature in this moment and sometimes it's a bit to swallow.

The comedown follows and is experienced as a literal rebirthing of the self. During the comedown a lot can happen including more release of tension, people often report things like interacting with their child self, or glimpses of past lives, or being other people, talking to the buddha or seeing him etc. All kinds of wild shit.

Depending on your energetic state prior to this full release you may or may not have had a full clearing of tension and may or may not need further work to reach equilibrium. It is in my opinion the need for further energetic work (more release dosing) is that which leaves some having reactivations. Reactivations are shifts back into the experience for mere moments often at the time of relaxation such as before or during sleep, I see it as an energetic shift working towards stabilization since the equalization was incomplete and the initiate did no further sessions.

-------

5-MeO-DMT does indeed or rather it can take you straight to source, but the toll is high and for many not easy to get through at all. It's not talked about as much because it is not well known and if you have seen ceremony, it can and often does turn most people off from wanting to "smoke toad venom". They see some person smoke toad venom and then scream, moan, thrash around, puke, etc... Before it is over they have seen enough.

5MEO is not for everyone, in fact it is often a last resort for trauma survivors, 5MEO is acutely effective in releasing held energies i.e., unprocessed emotions, repressed memories, held trauma energy and so on. This is due to the nature of 5mEOs primary function, it is a highly energetic event with high coherence in other words the energy is very focused on bringing the initiate down to their lowest energy state. It brings one back into equilibrium, your energetic state/chakras/etc. however you want to box it up.

Experientially, 5MEO will fully disassociate you in 10-15 seconds when vaporized, it comes for one's ego like a freight train, the come up can be absolutely terrifying, even horrifying, during the come up your default mode network (egoic structure) is getting shut down (ego dissolution) If you can let go, you will seamlessly transition into (every atom explodes) the infinite source as nothing and everything etc... If you cannot let go, however, you are going to have a bad time, how this plays out is unique to everyone, some can come back for more and some walk away traumatized further never to sit with 5 again.

What makes it so good at releasing trauma is the total annihilation of the ego/total shutdown of the default mode network and being fully dissociated with the body. In this state, all the mechanisms that repress memories or hold in emotions, traumas, held onto shit etc... are non-functioning, so whatever 5 didn't work through on the way up will be released on the way down and much of it during the peak.

You come back having experienced unification, and a rebirth of sorts also free of all the things that held onto shit was doing to you, the anger, the anxiety, etc... dropped onto a curb like trash... Sounds great right??

YOU JUST HAVE TO DIE FIRST, and that's why not everyone is jumping on board.

 


r/5MeODMT • • Aug 19 '20

Please follow the rules! If not, you will be banned! NSFW

87 Upvotes

Rules:

1. Absolutely no source talk! Sourcing is against Reddit's site-wide rules.

Note that the mods don't like the "no sourcing" rule either. However, we enforce the ban because:

  • we want more people to know about 5-Meo-DMT.
  • Reddit has a reach that is matched by few other forums.

If the mods fail to prevent sourcing here then the subreddit will be shut down altogether by the Reddit admins (as they've done to many other subreddits that didn't strictly prevent sourcing).

Please help make our jobs easier by not trying to source here.

Sourcing means discussing anything to do with acquiring 5-MeO-DMT. This includes, but is not limited to:

  • requesting, mentioning or giving sources of drugs or paraphernalia, whether legal or illegal.
  • reviews of vendors (positive or negative).
  • complaints about the lack of availability.
  • inviting potential sources to contact you offline.
  • discussing prices, quality, shipping costs, or anything else involved in the purchase of the drug.
  • messaging other members for a source.
  • veiled references to sources.

2. Please treat everyone with kindness and respect at all times. No insults, insinuations, or other rude comments allowed. Keep discussion civil, even if you are being baited.

3. Stay on topic please. If it's not immediately clear how your post relates to 5-MeO-DMT, then please include a brief blurb making the connection clear.

Moderators may remove any comments, posts, and users that violate these rules.


r/5MeODMT • • 21h ago

Looking to connect with people experienced in 5-MeO-DMT in Bavaria / Southern Germany

2 Upvotes

Hey! I'm based in Bavaria, southern Germany, and looking to connect with people experienced in 5-MeO-DMT. Would be cool to meet like-minded people, exchange experiences, and maybe explore or experiment together in a safe setting. Feel free to DM me!


r/5MeODMT • • 1d ago

How to ROA 5MeODMT-HCL? Can I convert it to freebase?

1 Upvotes

Hello,

How to ROA 5MeODMT-HCL? Can I convert it to freebase?

Thanks


r/5MeODMT • • 1d ago

Sex after full release

8 Upvotes

When I orgasm I’m having a big DMT surge, I’m guessing? The wisdom of release, let go, purge stagnant energy whenever and however I want to is connecting me to a deeper liberation and the benefits I’m experiencing are so delightful and unexpected. I’m guessing it’s also like an integration effect? or blasting open of gating channels reshaping what is possible for this vessel.

Intimacy is a space where I didn’t feel ‘broken’ before but I knew there was a whole world I was not available for.
I’m laughing with less inhibition like the chord was cut that restricted my playfulness. To be clear, I found myself quite playful and relaxed before. But there was a depth where I could touch the bottom and it felt Solid.

I’m louder when I’m having sex with a range of vocal releases that are not contrived. For decades I let myself be shaped by the integrated conditioning of how I should behave and so a forming and shaping that singed my tentacles of pleasure, of exploration, of Range!

And now the range is ignited and when I orgasm it’s everything I imagined it could be and all that I couldn’t imagine.

Wow. I want to make the most of all the possibilities and open all my channels that want to be safely opened. Two days ago I had an almost ‘too much’ day. Then I went and forest bathed and sucked up energy in my palms to cleanse and felt Monumental and almost like I needed to vomit and then I swam in the springs and felt like my whole being was breathing underwater.

Life in so many ways, feels new.


r/5MeODMT • • 2d ago

Awaken with 5 anyone?

4 Upvotes

Anyone have any experience with this program?


r/5MeODMT • • 2d ago

We are experiencing a seizure

4 Upvotes

For nearly 4 years several of us have been following the science, including a lot of evidence pointing to the idea that we are experiencing a ecstatic seizure.

A young researcher Haley Marie Dourron pointed out the similarities between observing and the descriptions of hundreds of people being served bufo/5meo and the descriptions from epileptics of ecstatic seizures.

But no one has had the ball’s to come out and just say it. I’ve read and seen most of the discussions by Blackburn and Timmerman but I never heard them say the magic words.

Just noticed Joel Brierre from FIVE finally said it out loud in a Psychedelics as Medicine 2025 Conference presentation for the Eden Foundation titled; 5-MeO-DMT, Rethinking the Human Brain
“What they saw happening simultaneously was the brain showing indications that it is in a deep state of anesthesia as well as in an epileptic seizure. Both ends of a very very very long spectrum happening simultaneously”

You can skip to 10:55 mark
https://youtu.be/TZzmm9oakDM?

Here’s the Haley Marie Dourron presentation I mentioned
https://youtu.be/5hjgWVczNlY?


r/5MeODMT • • 4d ago

Looking for safe, legal/regulated private clinics with experienced facilitators for 5-MeO-DMT Europe

4 Upvotes

Hi everyone,

I’m looking into experiencing 5-MeO-DMT for therapeutic/personal growth reasons, and I am specifically looking for options within Europe. Given the intensity of this substance, safety and privacy are my absolute top priorities.

I am searching for a private clinic or therapeutic center with highly experienced facilitators and medical staff on standby (operating legally, e.g., in countries like the Netherlands, Portugal, or Spain where specialized centers/retreats operate).

Does anyone have personal experiences or recommendations for reputable facilities in Europe that offer proper preparation, a controlled 1-on-1 private setting, and thorough integration support?

Any insights, reviews, or red flags to watch out for would be greatly appreciated. Thanks!


r/5MeODMT • • 3d ago

Was this 5-MeO-NMT or 5-MeO-DMT? Anadenanthera spp rootbark report

1 Upvotes

A few days ago, I had a very intense experience with 10 mg of crystals extracted from the stem bark of Anadenanthera colubrina, which I believe was 5-MeO-DMT-dominant. (Report:https://www.reddit.com/r/druggardening/s/aHPgsOMwC5)

Today, I conducted another bioassay with crystals extracted from the same genus, but this time using the root bark of an unidentified Anadenanthera species (possibly A. colubrina, although there were some A. peregrina trees nearby). I obtained around 30 mg of white crystals with little odor and smoked approximately 20 mg mixed with Sida rhombifolia in four large hits.

By the second hit, I was already experiencing a sensation very similar to my previous experience, but this time the visual effects involving blurring and "sharpening" were much more intense. The vibration that started in my body quickly became localized in my face, and I felt muscular pressure and tension throughout my entire face for the rest of the experience. By the third hit, both my body and the world around me were vibrating. After the last hit, I decided to lie down and close my eyes.

I felt my body vibrating as if I were experiencing an earthquake, in sync with the drums playing in the background. Unlike my previous experience, which was full of euphoria and a sense of meaning, this time I felt completely dissociated from myself. I wasn't euphoric or dysphoric, just neutral. I experienced strange visuals in the darkness behind my eyelids, but I can barely remember anything from the peak.

My face kept getting tenser, and my senses became increasingly alert. It's very difficult to put this into words. After who knows how long, I decided to open my eyes. The world looked strange, alien, completely different from what you would expect from DMT visuals. I couldn't keep my eyes open for long and returned to the world of amnesia with my eyes closed. Some time later, I tried getting up and opening my eyes again, but I was moving in slow motion, making meaningless movements, as if I were learning how to exist. I remained in this state, listening to the drums and trying unsuccessfully to get up.

After several attempts, I finally managed to stand up. My body felt heavy and sluggish, but in a way very different from what I experience with DMT. I managed to sit down after nearly falling and started documenting everything through messages in a group chat with friends. I was still dissociated and robotic, completely emotionless, with my memory of what I had just experienced almost entirely wiped out.

My memory gradually returned, but I can't remember anything from the middle of the experience. I don't feel like I died, as you might expect from a 5-MeO-DMT breakthrough, but I did experience this strange sensation of being "reborn" while still alive.

I haven't seen many reports about 5-MeO-NMT, but I've come across analyses showing that it can be the dominant alkaloid in certain parts of the plant. I haven't found any studies on the roots of Anadenanthera colubrina, while A. peregrina apparently has a 5-MeO-DMT-dominant alkaloid profile in this part of the plant.

Does anyone have any idea what this could have been? It was an interesting experience that I'd like to have again, but it wasn't euphoric or particularly emotionally significant. Much like the effects themselves, I feel neutral about the experience, just curious about how far this could go.


r/5MeODMT • • 4d ago

Need advices 5-MeO-DMT Benzoate Microdose Spray

3 Upvotes

Hello guys

I purchased some 5-Meo-DMT Benzoate Microdose Spray, each pump is 1mg.

I experienced once before some changa, no breaktrough or major trip, just few minutes of an intense but managable visions. And many times LSD/Shrooms

Now, what I should know before trying the spray?

I can't find anything like a guide or a tutorial for such dmt spray, only some randoms posts on reddit but not very indicative of things to do/ what to expect/ dosages etc.

Is anyone able to help me out?

Thanks in advance


r/5MeODMT • • 5d ago

When you experience ego dissolution, does the self actually disappear?

5 Upvotes

Hey everyone. I recorded a podcast with Jason K. Day at ICPR this year, the International Conference on Psychedelic Research. He’s a philosopher studying psychedelic experience who has worked with Dan Zahavi, known for his work on phenomenology and selfhood. I think many of you might find it interesting, especially if you’re into philosophy.

We talked about ego dissolution, particularly on 5-MeO-DMT, and whether it’s possible to be conscious with absolutely no sense of self. Jason’s argument is that even when your identity, personal history, and sense of being a separate person disappear, a radically minimal form of self-awareness remains. You might have no idea who or what you are, but the experience still feels like something to you. He draws on detailed analyses of trip reports to argue for this interpretation, though we also discussed how difficult it is to distinguish what people experienced from how they describe it afterwards.

We also covered why we need better descriptions of psychedelic experience before trying to explain it, whether different psychedelics share a common “style” of experience despite their very different effects, and how practice and skill affect our ability to navigate difficult trips. There’s also the question of what these experiences actually teach us, and how much we can infer from something feeling profoundly true.

But back to selfhood, which is what we focused on most. His main argument is that losing your usual sense of who you are doesn’t necessarily mean losing every form of self-awareness. In the reports he studied, people describe profound bliss or terror even when their identity and sense of separation have dissolved. He interprets this as evidence that some awareness of undergoing the experience remains, although almost everything that would ordinarily identify the subject has disappeared. In phenomenological terms, the claim is that ego dissolution preserves a radically minimal, pre-reflective self-consciousness, sometimes described as the “for-me-ness” of experience. In everyday language, you don’t need to think “I’m experiencing this,” or even know what “I” refers to, for the experience to be felt by you. The disagreement is whether even that basic feature can disappear while consciousness continues.

For those who’ve experienced deep ego dissolution, did all sense of being someone disappear, or was there still some awareness that the experience was happening to you? And do you think “minimal selfhood” captures something real about that state, or imposes a philosophical interpretation on it? Personally this take on selfhood very persuasive and aligns pretty well with my experiences.


r/5MeODMT • • 4d ago

Am I a masochistic god?

0 Upvotes

If I am the sole, eternal creative source, and I am the very abundance of all energies, and I can freely summon anything at any time,

why am I trapped in this sinister human frequency?


r/5MeODMT • • 5d ago

Jaguar 5 meo vape pen - Leaking

2 Upvotes

I made a jaguar pen two days ago, and was excited about using it for low dose therapeutic microdosing.

Two days later I see the liquid has lowered. It was already not a lot in there, just around 0.310 mg of PG and VG, and 48 mg of 5.

I've heard some liquid will go into the ceramic of the pen, which is normal, and doesn't mean it's gone. But it was also clearly leaking a bit.

I had just let the patron stand vertically, with the plastic protector cap on the bottom on. That plastic cap covers the screw threads which connects to the battery.

When I took that plastic cap off (which I probably should before connecting with the battery?), i saw some liquid coming out.

So i took off the protector cap and just put the patron onto the CCell vape pen battery.

I wonder if I have a time frame to use it, honestly. If if I'm going to get use of it, the time must be now I guess?

Can the content in the pen have become significantly more potent?

I prepared it to be 1:6. Just making sure it's not 1:2 or so, because then id be hesitant to inhale.

Can I assume it keeps leaking inside the pen right now? I didn't have a lot of jaguar, so this was all I had.

Appreciate your help!


r/5MeODMT • • 6d ago

The Sacred Synthesis

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0 Upvotes

This is a good conversation about how 5MeO can be used to deepen the intimacy between couples etc.


r/5MeODMT • • 8d ago

Concerned about the long-term psychological effects of Bufo

12 Upvotes

(5-MeO-DMT)

Hi everybody,

First of all, thank you in advance to everyone who takes the time to share their thoughts and experiences.

This December, I'll be attending a three-day ayahuasca retreat, where we'll also have the option to try Bufo.

While I believe this could be an incredibly valuable experience, I'm concerned about its potential long-term psychological effects.

I'm currently unemployed and in the process of starting my own business.

My main fear is that the experience might make me feel detached from my business ambitions or negatively affect my motivation, concentration, or intellectual abilities for weeks or even months.

I understand that this kind of detachment can sometimes be seen as a positive outcome, as it may help people reassess their priorities and their relationship with achievement and success.

However, I have a wife and two young children who depend on me, and I simply can't afford to become emotionally or intellectually unavailable for an extended period.

I'm not particularly worried about having a difficult experience during the ceremony itself. What concerns me most is the possibility of struggling to return to my normal level of functioning afterward.

I'd be especially interested in hearing from people who have experienced Bufo while dealing with significant professional or family responsibilities.

How long did it take you to feel completely back to normal? Did you notice any lasting changes in your motivation, ambition, or cognitive abilities?

Thanks a lot for sharing your experiences!


r/5MeODMT • • 7d ago

XUM SPIRT VAPE- HARDFIX TIMELINE - BETA TALK - m

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0 Upvotes

r/5MeODMT • • 8d ago

To whoever just DMd me

3 Upvotes

Hey there. Thanks for the heads up! Great moderating. 🙏🏼
Currently listening to 5 Integration by Martin Ball.
I forget who mentioned it but the QRI series is pretty banging too. Particularly the ones on The Formless Jhāna and Perils of The God-Head.
I had such a great experience Sunday. To have known that We Are for some time and be close to non-duality and then to experience the I AM is just…. Well, you know.
Anyway, thanks again for watching my 6.
Tycer


r/5MeODMT • • 9d ago

Breakthrough experience

27 Upvotes

Did 5meo at a clinic following ibogaine.

There was no terror but utter bliss going in. Inhaled 10mg and got close but then it faded...i was served 10mg more and I became everything and just laughed hysterically and felt spiritual bliss. This gave way to a primal scream and a release of rage I didn't even know I had. That scream came from the depths of my soul and was so visceral and cathartic.

There's been a tightness in my chest ever since about the age of 12 - which is when I started dealing with high anxiety. That tightness just went away. It's seven days later and there is still no tightness.

10/10 would recommend.


r/5MeODMT • • 9d ago

My recent experiences have put me in touch with my severe OCD

8 Upvotes

Hi all,

I just want to share my recent experiences with you. I am seeking some insight.

I've done 5meo 3 times now, always with a guide.

I have pretty debilitating OCD, which leads me to do constant status checks in with myself about how I'm doing anything whatsoever. If I wake up in the morning I go in and think 'did I get enough sleep?', and if I did I go on to the next thing 'did I eat right yesterday?' it goes on and on. I find this in my therapy for example by always doubting whether I've engaged deeply enough with the time my therapist has provided me with. There's always a sense of disappointment in myself. This is the work I have been doing pretty intensely recently. This OCD has manifested in my sessions by making me feel like I've used the medicine incorrectly, like I hadn't taken enough, or, when i do take enough, to even feel like I'm not sufficiently engaging with the opportunity it's presenting to me.

The first time I did it I took it in and immediately felt pretty uncomfortable. I hadn't slept the night before so I became very conscious of my heart beating and my head suddenly felt very hot. I came out of it and was pretty disappointed. I told my guide and he said that I was fighting it and that I needed to surrender. So I go in again, this time taking a little more, and as I feel it come on i decide to surrender to whatever the hell it is. My experience immediately became intensely uncomfortable. I suppose I began to fight it again. I started screaming and groaning. My guide insisted again "Surrender...surrender..." So i sit back up and do some deep breathing, surrendering to the medicine and holy shit it hit me so hard and I just started crying and crying for 30 minutes. I felt like I was washed totally clean. I was crying and, feeling my ego surface in the vein of OCD, laughing at myself, really laughing at myself for how silly I was. It was just one to the other, crying and laughing.

I did it for the third time the other day and was surprised with how differently I encountered this part of myself. I'm aware that nothing will ever be like that first trip, and, as I learned from my second time which I haven't detailed here, it's wise to not chase the dragon or have any expectations. This third time, using what I learned from my last session, I inhaled enough into my lungs and held it in and surrendered when it came on. It started working my body, making me writhe and groan. (How I do love it that it does this to me). The OCD came on and I was suddenly very afraid and self-doubting, just like I mentioned above. I tell my guide how scared I am and that I feel I'm doing it wrong. He says "You are not the fear. You are the awareness of your fear. The moment you become aware of it you're not afraid anymore. You're simply the awareness of all the fear that is within you." Hearing this felt revelatory. He told me that what the medicine was doing for me was baring my ego, making that part of myself as visible as possible. So I tried to become a witness to this compulsion but, par for the course, I immediately started critiquing that witnessing itself, as if I wasn't ever going deep enough or so on and so forth. You get the idea. The whole thing became this cycle of fear/doubt--->witnessing fear/doubt---->fear/doubt about witnessing---->witnessing fear/doubt about witnessing--->witnessing fear/doubt about witnessing witnessing. I am reminded of the Ouroboros. Altogether, I still feel cleansed and that I've come a little bit closer to some kind of inner light that's always been present within.

I am wondering what you all make of this. I am not involved with the DMT community but I haven't heard anyone else having an experience like this. Another thing thats interesting is that I don't get visuals whenever I've done it. I don't think that this is a factor of my not inhaling enough because I feel like i've been hit by a train and my guide did a similar amount last time at a certain point and had visuals during his experience. I also like to read about this sort of thing so if you know of any articles or things to share I would appreciate that as well.

Thanks


r/5MeODMT • • 10d ago

Djanas and 5-meo-dmt

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3 Upvotes

As only Andres Gomez Emilsson and QRI can here is an interesting study.

I wish I could have been there.


r/5MeODMT • • 11d ago

Anyone get answers to their questions on their trip?

2 Upvotes

I’ve never taken it before but would like to. I’ve read that the concept of questions and answers just kind of collapse when you take a high dose.

I guess the main thing I want to know about is death. I feel like death is an illusion. I just wonder whether when we die we remain eternally in a divine state or whether we are reborn into something new. I’m just super curious about that.

Were you able to get any answers while taking it?

thanks, peace & love <3


r/5MeODMT • • 11d ago

250 mg per 1 mL, or 300 mg per 1 mL?

3 Upvotes

It’s a never-ending story. Two months ago, I started taking 5-MEO-DMT and tried to recreate the experience I’d had with a facilitator. But it didn’t work out. I mixed 100 mg per 1 mL, and the onset was slow—it just wasn’t right at all. Recently, I realized that the problem wasn’t just the cartridge, but the dosage itself. I mixed 200 mg per 1 mL, and it’s much better. The experience is more like the first one, but it still feels like too little to me. Right now, I’m wondering if 250 mg will be enough for a breakthrough, or if I should go straight to 300 mg per 1 mL. I plan to start with a cartridge containing 200 mg to begin with, and once I reach about 12 seconds per draw, I’d switch to a cartridge with 300 mg or 250 mg per 1 ml. What do you think? I’d say I’m on the right track.


r/5MeODMT • • 11d ago

Nasal spray

2 Upvotes

Greetings phyconaughts.

I have a gram of 5 that can be turned into a nasal spray.

I have never gone this route before.

Just wondering what a good mix ratio would be.

How much bacteriostatic water to 1 g should I add?


r/5MeODMT • • 12d ago

Why does PsychonautWiki say that snorting 5-MeO-DMT is discouraged?

3 Upvotes

They say the following: “When taken in its synthetic powder form, 5-MeO-DMT is typically vaporized, but can also be insufflated (although this is discouraged)…”

I’ve never tried 5-MeO-DMT but have some FB coming and was hoping to turn it into a salt as I suuuuck at successfully smoking things.


r/5MeODMT • • 12d ago

5meo/thegodmolecule

0 Upvotes

Just a quick question for anyone that has tried the molecule.

I have recently been able to obtain 2 grams of the substance but was told that he had used 1.5 grams for a breakthrough.

Having done my own research this should be a lethal amount to take.

For my own trip what dosing should I do for a break through with it ending horribly

Thanks