44YO , 5”11 , 210 pounds, Male

I’m into my first ever trt dose and I just finished week 1 at 75mg a week which is divided into two shots a week with my doctor.

Am I good to start Reta at 2mg next week along with the trt injection you think? Or should I wait for the trt to fully saturate first in my body and then introduce Reta?

I’ve done Reta before several times just in case that info is needed. I’m just curious if Reta will interfere with me knowing what med is actually doing with or am I overthinking things ?

Thanks guys

Hello, after 2 full blood panels I got diagnosed with Secondary hypogonadism (doctor thinks so). I got prescribed 25mg Clomid EOD for 1 month and then we retake the blood test. Thing is, after 3 weeks in, I feel the same, even shittier than before. No energy, sleeping a lot, no motivation and I keep getting random migraines.

Do you have any experiences with Clomid and do you think it's just piss in the wind before getting treated with TRT?

I am 23M, 96KG.

Blood results BEFORE starting Clomid:

Total T: 7.32 nmol (210ng)
E2: 92 pmol
FSH: 5.4 mUI/mL
LH: 6.2 mUI/mL
SHBG: 16.6 nmol

I started TRT this December while still battling a weakness towards excessive drinking. The first picture is right when I started, The second picture was around July. I started the journey at 17% body fat, down to now 8.4%.
I've done 100mg a week until only recently moving up to 110mg.
Now, bear in mind I was active before TRT - I've always gone to the gym and always played soccer.

Thanks to the TRT I can workout harder, longer and do multiple activities in a day and actually see results.
My routine is gym 7days a week when consistent. Soccer 3 times a week, pickleball several hours a week and then I run and hike all the time as well. I'm a little obsessive, but exercising is what truly makes me happy.
I did not get on to TRT for gym results, they are just an awesome side effect.
Before TRT - I drank like a fish, I was in AA, I took antidepressants, anxiety meds and frequented therapy. Today, none of these issues have remained in my life.

No zits, no hair loss or thinning and all my previous Injuries have completely disappeared. Meaning - no knee brace when I play soccer.
(I was secretly hoping to actually grow some chest hair.... but who cares)

If you're reading this contemplating if you should get on TRT - I'm telling you to do it! It changed every aspect of my life.

Thanks for reading.

63M, 6-1, 225lb, CPAP. Started TRT on 8/28/26 with baseline T of 302 and HCT of 45.8%. Taking 84 mg/week test-c SQ, split MWF, without HCG or AI.

First labs on 10/12 showed total T of 773 (Monday trough), free T of 122.9, E2 of 36, prolactin of 17, and HCT of 50.6% (a 4.8 increase in just 45 days). I’m feeling noticeably better in terms of energy, strength, and libido. Donated whole blood on 10/14 because of the rapid HCT increase and am thinking about reducing to 60 mg/week, still MWF, to deal with HCT.

Anyone experienced this kind of HCT increase on a relatively low dose? Did reducing your dose bring it down, or did it eventually stabilize?

My question is - Do you require less protein for muscle when on TRT?

6’ 235 lbs. On about 100/wk, trying to lose weight while gaining muscle if possible, lifting weights like 5/6 times per week, 10k steps. Trying to get 200g protein while keeping calories below 2500. I feel like im not getting enough carbs. Thinking about dropping some protein for extra carbs. Thoughts and experiences?

I’m a 51‑year‑old guy in good shape who trains hard (CrossFit + lifting + conditioning almost daily). I’ve dropped `20LBS over the past 4 months and sit around 215 lbs now. I eat clean, don’t drink, don’t smoke, and generally take care of myself, but I’ve been dealing with low libido, lower drive, slower recovery, and just not feeling like I’m firing on all cylinders.

I’ve been digging into my labs and trying to understand whether TRT makes sense for me, but the risk/reward feels complicated.

My recent biomarkers :

• Total Testosterone: 518 → 646 → 702 ng/dL (normal range)
• Free Testosterone: consistently low across multiple methods
• SHBG: 60–63 nmol/L (high)
• FSH: elevated
• LH: normal
• Estradiol: 35 pg/mL (normal)
• Prolactin: 3.2 ng/mL (normal)
• PSA: 3.0 → 2.39 (borderline but stable)
• Lp(a): 75.6 nmol/L (mildly elevated)
• Lipids, kidney, liver, thyroid, inflammation: all normal
• Sleep: 4–6 hours/night
• Training load: high
• Stress: high

So I’m in this weird spot:
Normal total T, low free T, high SHBG, elevated FSH.

Not classic hypogonadism - more like SHBG-driven low free T with partial age-related testicular decline.

My hesitation:

I’ve been researching TRT heavily. I understand the commitment, the suppression, the monitoring, and the potential risks (hematocrit, PSA, estradiol volatility, cardiovascular stuff). I’m not anti‑TRT - I just want to make a smart decision.

My Hone consultation this morning:

I had a remote consult with Hone. The doctor basically said:

• My total T is “falsely good” because SHBG is high
• Free T is what matters, and mine is low
• Estradiol is “high-normal” and should be lowered
• SHBG is “killing my free T”
• He recommended immediate TRT
• Dose: 0.4 mL (80 mg) twice weekly
• Plus anastrozole 1 mg twice weekly starting day one
• Said he’d “bet his career” my estradiol will go high without an AI
• Mentioned enclomiphene but clearly preferred TRT
• Said TRT would help libido, energy, gym performance, cognition
• Follow-up labs at 90 days

I’m not saying he’s wrong - just that this was a very aggressive plan compared to what I expected. Especially the AI at initiation.

Where I’m stuck:

I’m trying to weigh:

• The desire to feel better
• The fact that my free T is genuinely low
• The risks tied to PSA and Lp(a)
• The commitment of TRT
• Whether I should try enclomiphene first
• Whether lifestyle changes could lower SHBG
• Whether starting TRT at a lower dose and monitoring closely is a safer path
• Whether I’m overthinking this entirely

My question for the community:

For guys who’ve been in a similar biomarker situation — normal total T, low free T, high SHBG - how did you decide between TRT, enclomiphene, or waiting?

If you’ve gone the TRT route, how did you weigh the risks?

If you’ve tried enclomiphene, did it actually help free T and symptoms?

If you were in my shoes, what would you want to know before making the call?

I’m not looking for medical advice - just real-world experience and perspective.
This feels like a big decision, and I want to make it deliberately.

Thanks in advance.

I inject subq 3x a week. Same days, same times, haven't changed the dose in a while. Got my latest labs back and free T was quite a bit different from last time even though total T hadn't moved nearly as much.

Then I realized the first blood draw was the morning after an injection and this one was right before my next one.

Clinic mentioned adjusting my dose and I asked if we should maybe repeat the labs under the same conditions first. Didn't really get an answer on that. So I ordered total/free T and sensitive E2 through Goodlabs and I'm getting the draw done before my next injection again. Would rather have something consistent to compare before messing with a protocol that's been working fine. For the guys injecting 3x a week, are you always getting bloodwork done at trough?

Also curious how much the free T assay matters when comparing results. I log my injections, sleep and gym sessions religiously. Can't believe the blood draw timing is what I managed to screw up.

Last week I met with my urologist again and was told I was a hyperresponder to testosterone.

My question is, get wrecked beta cucks. How’s it feel to not even be able to efficiently metabolize and use testosterone. Imagine having a bitch body that doesn’t even want to be a man.

Good luck!

Been on the juice since June. Love the way I feel. Everything in my life is better… except erectile dysfunction and no libido.

Blood work is solid. Including prolactin, e2, free test, etc. The only time I have any libido and functional erections is when I completely crash my estrogen with anastrozole to the point of achy and cracking joints

Both the provider and I are clueless.

Going to start Enclomiphene 12.5mg daily while stopping injections in hopes of getting my body back to “normal”

Anyone have experience with this?

I should take 500 ui twice a week. This pen have 26 clicks so i should inject " 2 clicks ". But 2 clicks is not marked as dose on pen. It shows "dot" that is mentioned in instruction as "preparation dose before first use" . What should i do? Do you guys have any experience with this device

Looks like you can just buy Ancillaries on Talon wellness website now does anyone know if this is real or do you still need to jump through all the hoops ?

41M, been on testosterone cypionate IM for about two years. Recently switched from 200mg every two weeks to 100mg every Monday morning against my Dr’s order. He wouldn’t budge on me pinning every two weeks.

My previous labs, taken four days after a 200mg injection, showed:
Total T: 881 ng/dL
Free T: 35.1 (flagged high)
Hemoglobin: 16.1

I’ve been on the new weekly schedule for about two months and have noticed an increase in libido. But I’m sure I’m missing other markers.

I’m wondering how my current levels might compare to my previous results.

Would Thursday afternoon (3.5 days after injection) be the best time to test? Should I expect similar numbers, or would the smaller, more frequent injections produce noticeably different results?

Anyone made this switch and have labs to compare? Also curious whether your libido stays consistent or fluctuates throughout the week.

Does anyone have experience ditching their TRT Clinic and switching to just using Amazon Pharmacy or a local Pharmacy to refill prescriptions?

I am tired of paying $100 a month for a vial of test which should cost at most $30 with insurance. The “check-ins” are pretty useless and bloodwork is still a pain in the ass.

Edit for clarification: I will still obviously do blood work after the switch - was just making the point that for the amount they charge you they should really make it easier.

Any advice on how to retain the prescription without paying for an online clinic? I’d like to be able to keep having it shipped to me every 8-10 weeks.

Is this something a normal doctor can prescribe and I can just order on Amazon?

Thanks in advance!

What do you think about my blood results. Should I start with trt?
I'm 43, active, more ore less dialed up with food, but for the last few years I'm having all the low T simptoms, the one that bothers me the most is the downfall of the libido.
Wanna start with 100mg cyp weekly and see where this goes.

Had an appointment today for a hernia ive had for years. Figured I would just ask him while I was there. He didnt even hesitate and said yeah no problem.

He just had me send over my original labs from when I was low and my current labs on my current dose and he sent the script over and its already filled. Since its a controlled substance I had to do a piss test and do bloods.

Ordered a follow up in 1 month to see how its going.

Saw the script in the pharmacy website and it looks like they are prefilled 150mg shots called andrenyx. Since I was currently on once a week shots that what he prescribed. Anyone ever hear of these or use them?

I’m thinking of starting testosterone injections, they’ve been prescribed already, but I’m feeling conflicted because my friend said it’s a stupid idea. I want better energy, focus, and libido. Muscle gains would be a nice side effect as well haha. What do you guys think?

Also if it’s worth mentioning, I took trt in the past and felt 10 times better.

I’m Brand new into my research and consideration of taking trt, what should I look into/research/consider?

Can I have my insurance pay for my trt if I'm already on it?

I've been on it for 3 years, I just got insurance through my job. My levels are obviously currently not low.

Any advice

Hi guys, i am just wondering how long you use your hcg vials if they are already reconstituted. As I only use 3x 250iu per week and I have 5000 iu Vials it's a big waste if I only use them for 28 - 30 days as mentionned in chatgpt

I am a 40M. Started on trt ~8weeks ago primarily for mood, and so far I am happy with the result. I started on testosterone enantate 250 mg/mL 0.25mL (62.5mg) twice weekly. I got my first follow-up bloods and I am just a little hesitant to follow the clinic’s advice on my dose reduction. My bloods are below and I have given both SI and US units.

SI Units

US Units

All other labs are looking OK, it is just the hormone levels I am worried about.

My goal was to boost me to the higher end of normal (35nmol/L / 1000ng/dL), but I have gone way above that. My thoughts are that I went up 38.8nmol/L (1,119ng/dL) with a 125mg weekly dose. I was really only wanting to go up by ~16nmol/L (452ng/dL). So my rudimentary maths (if there is a linear-dose relationship), would be that is 125mg weekly results in 38.8nmol/L increase, a dose of ~50mg weekly would give the increase of 16nmol/L I was targeting.

The clinic has only suggested a dose change to 100mg weekly (20% reduction) which I am concerned is not enough. I don’t have the personal experience to know if there is that predictable linear-dose reduction and was hoping someone could impart some wisdom. Should I go with the reduction to 100mg weekly, or go to 50mg?

Open enrollment for health insurance is coming up and there is a plan avaliable that will fund 1k into an HSA. According to AI, I can pay my trt clinic with my HSA card. Somethings like shipping don't apply, but medication, blood work are allowed.

Does this sound legit?

Hello everyone, I've been using TRT for about 6weeks, my dosage are 150mg enanthate... My pre trt levels of testosterone were around 10nmol ( 288ng/dL ), now after 6weeks of TRT my levels are 11.4nmol ( 335 ng/dL ). I'm injecting 3x50mg weekly, on monday night, wednesday night and saturday in the morning... test done on monday morning 48h after last injection. Is this normal really hoped for better results and a lot higher testosteron levels.

If excess testosterone is converted to estrogen, then what happens to that excess when an AI is used?